Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine

Qin Liu; Shun-Chun Wang; Kan Ding

doi:10.1016/S1875-5364(17)30093-6

Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine

Chin J Nat Med. 2017 Sep;15(9):641-652. doi: 10.1016/S1875-5364(17)30093-6.

Authors

Qin Liu¹, Shun-Chun Wang², Kan Ding³

Affiliations

¹ Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Glycochemistry and Glycobiology Lab, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
² Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: shunchunwang@126.com.
³ Glycochemistry and Glycobiology Lab, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. Electronic address: dingkan@simm.ac.cn.

PMID: 28991525
DOI: 10.1016/S1875-5364(17)30093-6

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the loss of patients' memory and their cognitive abilities and the mechanism is not completely clear. Although a variety of drugs have been approved for the AD treatment, substances which can prevent and cure AD are still in great need. The effect of polysaccharides from traditional Chinese medicine (TCM) on anti-AD has gained great progress and attained more and more attention in recent years. In this review, research advances in TCM-polysaccharides on AD made in this decade are summarized.

Keywords: Alzheimer's disease; Polysaccharides; Traditional Chinese medicine.

Publication types

Review

MeSH terms

Alzheimer Disease / drug therapy*
Animals
Drugs, Chinese Herbal / administration & dosage*
Humans
Medicine, Chinese Traditional
Plants, Medicinal / chemistry*
Polysaccharides / administration & dosage*

Substances

Drugs, Chinese Herbal
Polysaccharides