To explore the relationship between brachial ankle artery pulse wave velocity of the (baPWV) in different estimation GFR (eGFR) groups and atherosclerosis.In 2010, 2012 and 2014, eGFR and baPWV were detected in 1 427 healthy persons.As eGFR level decreased, baPWV increased accordingly with higher proportion of baPWV ≥1 400 cm/s.The percentage of eGFR lower than 60 ml·min-1·1.73 m-2 was similar in subgroups with different baPWV.However, the proportion of eGFR reduction≥30% decreased according to the elevation of baPWV.Multivariate logistic regression analysis indicated the lower the eGFR, the higher the risk of atherosclerosis.Low eGFR is an independent risk factor for atherosclerosis.
通过观察不同估算GFR(eGFR)者的臂踝动脉脉搏波传导速度(baPWV)，探讨其与动脉硬化的关系。选2010、2012、2014年健康体检者1 427例，检测eGFR和baPWV。随着eGFR稳定水平降低，baPWV≥1 400 cm/s的比例逐渐增高，baPWV均呈增高趋势。不同baPWV者eGFR<60 ml·min－1·1.73 m－2的比例差异无统计学意义，但eGFR下降≥30%的比例随baPWV水平的升高呈上升趋势。随着baPWV水平升高，eGFR均呈下降趋势。多因素logistic回归分析显示，eGFR水平越低发生动脉硬化的风险越升高，eGFR低稳定者是发生动脉硬化的独立危险因素。.
Keywords: Atherosclerosis; Brachial ankle pulse wave velocity; Chronic renal injury; Estimated glomerular filtration rate.