Physical activity and suicidal ideation: A systematic review and meta-analysis

J Affect Disord. 2018 Jan 1:225:438-448. doi: 10.1016/j.jad.2017.08.070. Epub 2017 Aug 24.

Abstract

Background: A potential approach to suicide prevention that has not been closely examined, but which holds promise in terms of widespread dissemination without major side-effects, is physical activity (PA). This systematic review and meta-analysis set out to: (a) explore associations between PA and suicidal ideation (SI) levels, and (b) investigate the effect of PA interventions on SI.

Methods: Major electronic databases were searched from inception up to 05/2017 to identify quantitative studies reporting an association between PA and SI. A quantitative correlates synthesis and random effects meta-analysis were conducted.

Results: Fourteen of 21 studies in adults (67%) (n = 130,737), 7/14 (50%) in adolescents (n = 539,170) and 2/3 (67%) in older adults (n = 50,745) found a significant negative association between PA- and SI-levels. Pooled adjusted meta-analysis of 14 effect sizes over eight studies and 80,856 people found that those who were "active" versus those who were "inactive" were less likely to have SI (OR = 0.87, 95%CI = 0.76-0.98). Additionally, meeting PA guidelines conferred a significant protective effect against SI (OR = 0.91, 95%CI = 0.51-0.99, P = 0.03; N studies = 3, n people = 122,395), while not meeting guidelines was associated with increased SI (OR = 1.16, 95%CI = 1.09-1.24, P < 0.001; N = 4, n = 78,860). Data from the intervention studies (N = 3, n = 121) was mixed and limited.

Limitations: Our findings are based mainly on cross-sectional studies, while the majority of studies did not include a rigorous physical activity assessment.

Conclusions: The current study suggests that higher PA levels are associated with lower SI. However, the associations observed need to be confirmed in prospective observational studies and controlled trials.

Keywords: Mortality; Physical exercise; Suicide.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Attitude to Health
  • Cross-Sectional Studies
  • Exercise / psychology*
  • Health Behavior*
  • Humans
  • Middle Aged
  • Motor Activity
  • Prospective Studies
  • Suicidal Ideation*
  • Suicide / psychology
  • Suicide Prevention*
  • Young Adult