Maxillomandibular advancement as the initial treatment of obstructive sleep apnoea: Is the mandibular occlusal plane the key?

Int J Oral Maxillofac Surg. 2017 Nov;46(11):1363-1371. doi: 10.1016/j.ijom.2017.07.003. Epub 2017 Jul 29.

Abstract

Maxillomandibular advancement (MMA) can be effective for managing obstructive sleep apnoea (OSA); however, limited information is available on the predictor surgical variables. This study investigated whether normalization of the mandibular occlusal plane (MOP) was a determinant factor in curing OSA. Patients with moderate or severe OSA who underwent MMA were evaluated by preoperative and postoperative three-dimensional (3D) scans and polysomnograms. The postoperative value of MOP and the magnitude of skeletal advancement were the predictor variables; change in the apnoea-hypopnoea index (AHI) was the main outcome variable. Thirty-four subjects with a mean age of 41±14years and 58,8% female were analysed. The Epworth Sleepiness Scale (ESS) was 17.4±5.4 and AHI was 38.3±10.7 per hour before surgery. Postoperative AHI was 6.5±4.3 per hour (P<0.001) with 52.94% of the patients considered as cured, and 47.06% suffering from a mild residual OSA with ESS 0.8±1.4 (P<0.001). 3D changes revealed a volume increase of 106.3±38.8%. The mandible was advanced 10.4±3.9mm and maxilla 4.9±3.2mm. MOP postoperative value was concluded to be the best predictor variable. Treatment planning should include MOP normalization and a mandibular advancement between 6 and 10mm. The maxillary advancement would depend on the desired aesthetic changes and final occlusion.

Keywords: counterclockwise rotation occlusal plane; mandibular distraction osteogenesis; mandibular occlusal plane; maxillofacial surgery; maxillomandibular advancement; obstructive sleep apnoea syndrome; orthognathic surgery; sleep-disordered breathing.

MeSH terms

  • Adult
  • Aged
  • Cephalometry
  • Electroencephalography
  • Electromyography
  • Electrooculography
  • Female
  • Humans
  • Imaging, Three-Dimensional
  • Male
  • Mandibular Advancement*
  • Maxilla / surgery*
  • Middle Aged
  • Polysomnography
  • Prospective Studies
  • Sleep Apnea, Obstructive / diagnostic imaging
  • Sleep Apnea, Obstructive / surgery*
  • Surgery, Computer-Assisted*
  • Tomography, X-Ray Computed
  • Treatment Outcome