Procedures of Necropsy and Tissue Sampling

Methods Mol Biol. 2017:1641:71-100. doi: 10.1007/978-1-4939-7172-5_3.

Abstract

Necropsy is a major step of most studies using laboratory animals. During necropsy, tissue and organ noticeable grossly changes should be recorded and critical tissue samples may be stored for the subsequent evaluation. It is therefore important that the personnel in charge of this key experimental step to be adequately trained and aware of the study endpoints.

Keywords: Histology; Histopathology; Macroscopy; Mouse; Necropsy; Rat; Rodents; Sampling.

MeSH terms

  • Animals
  • Animals, Laboratory
  • Autopsy / methods*
  • Female
  • Humans
  • Male
  • Mice
  • Rats