Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release

Sci Rep. 2017 Jul 12;7(1):5259. doi: 10.1038/s41598-017-05693-3.

Abstract

Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-infrared active silica-coated gold nanostars (GNS) decorated by silver nanoparticles (AgNP). This modular approach also enables us to unravel static and photo-activated contributions to the overall antibacterial performance of the surfaces, demonstrating a remarkable synergy between these two mechanisms. Complementary microbiological and imaging evaluations on both planktonic and surface-attached bacteria provided new insights on these distinct but cooperative effects.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology*
  • Bacteria / drug effects*
  • Bacteria / radiation effects
  • Coated Materials, Biocompatible / chemistry*
  • Gold / chemistry
  • Lasers*
  • Metal Nanoparticles / chemistry*
  • Silicon Dioxide / chemistry
  • Silver / chemistry
  • Surface Properties

Substances

  • Anti-Bacterial Agents
  • Coated Materials, Biocompatible
  • Silver
  • Gold
  • Silicon Dioxide