Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding

Jiping Yang; Jingyi Li; Keiichiro Suzuki; Xiaomeng Liu; Jun Wu; Weiqi Zhang; Ruotong Ren; Weizhou Zhang; Piu Chan; Juan Carlos Izpisua Belmonte; Jing Qu; Fuchou Tang; Guang-Hui Liu

doi:10.1038/cr.2017.86

Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding

Cell Res. 2017 Sep;27(9):1178-1181. doi: 10.1038/cr.2017.86. Epub 2017 Jul 7.

Authors

Jiping Yang^{1

2

3}, Jingyi Li^{1

4

5

6}, Keiichiro Suzuki⁷, Xiaomeng Liu^{4

6}, Jun Wu^{7

8}, Weiqi Zhang^{1

2

5}, Ruotong Ren^{1

2

5}, Weizhou Zhang⁹, Piu Chan^{5

10}, Juan Carlos Izpisua Belmonte⁷, Jing Qu^{2

3}, Fuchou Tang^{4

6

11}, Guang-Hui Liu^{1

3

5

10}

Affiliations

¹ National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
² State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
³ University of Chinese Academy of Sciences, Beijing 100049, China.
⁴ Beijing Advanced Innovation Center for Genomics (ICG), Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, College of Life Sciences, Peking University, Beijing 100871, China.
⁵ National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital of Capital Medical University.
⁶ Biomedical Institute for Pioneering Investigation via Convergence, Peking University, Beijing 100871, China.
⁷ Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
⁸ Universidad Católica San Antonio de Murcia (UCAM) Campus de los Jerónimos, N 135 Guadalupe 30107 Murcia, Spain.
⁹ Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.
¹⁰ Beijing Institute for Brain Disorders, Beijing 100069, China.
¹¹ Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Adult Stem Cells / cytology*
Adult Stem Cells / metabolism
Base Sequence
Carcinogenesis / pathology
Cells, Cultured
Gene Editing
Genetic Enhancement*
Human Embryonic Stem Cells / metabolism
Humans
Nucleotides / metabolism*

Substances

Nucleotides

Publication types

MeSH terms

Substances

Grants and funding