[The 2016 update of the S3 guideline for malignant tumours of the ovary : Role of pathology in diagnosis, therapy and clinical management of epithelial tumours]

Pathologe. 2017 Jul;38(4):331-344. doi: 10.1007/s00292-017-0310-0.
[Article in German]

Abstract

Tumor stage, residual postoperative tumor, histological type and grading are considered among the main prognostic parameters in the consensus-based recommendations in the new S3 guidelines for diagnosis, treatment and clinical follow-up of malignant tumours of the ovary. Based on the 2014 update of the WHO Classification of Tumours of the Female Reproductive Organs this article summarizes the most significant changes. For example now the same TNM and FIGO classification applies for tumours of the ovary, peritoneum or fallopian tube. Noninvasive implants of serous borderline tumours are now named implants. In contrast, invasive implants are regarded as low-grade serous carcinoma. By presenting the current background information, we want to provide a basis for discussion, regarding more detailed consensus recommendations for pathologists and clinicians in the future.

Keywords: Classification; Histology; Immunohistochemistry; Molecular pathology; Prognosis.

MeSH terms

  • Fallopian Tube Neoplasms / classification
  • Fallopian Tube Neoplasms / diagnosis
  • Fallopian Tube Neoplasms / pathology
  • Fallopian Tube Neoplasms / therapy
  • Female
  • Germany
  • Humans
  • Immunohistochemistry
  • Neoplasm Staging
  • Ovarian Neoplasms / classification
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / therapy*
  • Peritoneal Neoplasms / classification
  • Peritoneal Neoplasms / diagnosis
  • Peritoneal Neoplasms / pathology
  • Peritoneal Neoplasms / therapy
  • Practice Guidelines as Topic
  • World Health Organization