Reversible Cerebral Vasoconstriction Syndrome Presenting with Transient Global Amnesia

Intern Med. 2017;56(12):1569-1573. doi: 10.2169/internalmedicine.56.7460. Epub 2017 Jun 15.

Abstract

A 65-year-old man who had been diagnosed with transient global amnesia (TGA) 15 years previously was admitted to hospital with complaints of amnesia and headache. His symptoms improved on day-2. The initial brain MRI and electroencephalography findings were normal. He was diagnosed with a recurrence of TGA and discharged. However, he returned with right leg weakness and complained of a thunderclap headache. MRI demonstrated subarachnoid hemorrhage and multifocal segmental narrowing of the left posterior cerebral artery (PCA) and large intracranial arteries, and he was diagnosed with reversible cerebral vasoconstriction syndrome (RCVS). He was discharged on day-30 without any neurological deficits. This case suggested that TGA should be interpreted as one of the symptoms of RCVS or a prodromal symptom of RCVS.

Keywords: reversible cerebral vasoconstriction syndrome; subarachnoid hemorrhage; thunderclap headache; transient global amnesia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amnesia, Transient Global / complications*
  • Headache Disorders, Primary
  • Humans
  • Male
  • Posterior Cerebral Artery*
  • Subarachnoid Hemorrhage / diagnosis*
  • Subarachnoid Hemorrhage / etiology
  • Syndrome
  • Vasoconstriction*