Characterization of Phenolic Compounds from Early and Late Ripening Sweet Cherries and Their Antioxidant and Antifungal Activities

J Agric Food Chem. 2017 Jul 5;65(26):5413-5420. doi: 10.1021/acs.jafc.7b01409. Epub 2017 Jun 23.

Abstract

Early and late ripening sweet cherries were characterized for phenolic acids, and also their antioxidant capacity and potential antifungal effects were investigated. Free, conjugated, and bound phenolics were identified and quantified using ultra performance liquid chromatography-tandem mass spectrometry. Our results indicated that the early ripening cultivars contained higher free phenolic acids, which was positively related to remarkable antioxidant properties and the inhibition effects on Alternaria alternata and tenuazonic acid (TeA) accumulation. However, conjugated phenolics of the late ripening cultivars, mainly including caffeic, 2,3,4-trihydroxybenzoic, p-coumaric, and pyrocatechuic acids, achieved the highest antifungal effects and almost completely inhibited the A. alternata and TeA production. 2,2-Diphenyl-1-picrylhydrazyl testing and ferric ion reducing antioxidant power assay showed strong positive correlation with total phenolics and specific phenolics such as free epicatechin and conjugated 2,3,4-trihydroxybenzoic acids and also with antifungal activity. Results from this study provide further insights into the health-promoting phenolic compounds in sweet cherries.

Keywords: antifungal activity; antioxidant; early and late ripening sweet cherries; mycotoxin; phenolics.

MeSH terms

  • Alternaria / drug effects
  • Alternaria / growth & development
  • Alternaria / metabolism
  • Antifungal Agents / chemistry*
  • Antifungal Agents / pharmacology
  • Antioxidants / chemistry*
  • Antioxidants / pharmacology
  • Chromatography, High Pressure Liquid
  • Fruit / chemistry
  • Fruit / growth & development
  • Mycotoxins / metabolism
  • Phenols / chemistry*
  • Phenols / pharmacology
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology
  • Prunus avium / chemistry*
  • Prunus avium / growth & development
  • Tandem Mass Spectrometry

Substances

  • Antifungal Agents
  • Antioxidants
  • Mycotoxins
  • Phenols
  • Plant Extracts