Treatment outcomes of MDR-TB and HIV co-infection in Europe

Cecile Magis-Escurra; Gunar Günther; Christoph Lange; Sofia Alexandru; Neus Altet; Korkut Avsar; Didi Bang; Raisa Barbuta; Graham Bothamley; Ana Ciobanu; Valeriu Crudu; Manfred Davilovits; Martin Dedicoat; Raquel Duarte; Gina Gualano; Heike Kunst; Wiel de Lange; Vaira Leimane; Anne-Marie McLaughlin; Inge Muylle; Veronika Polcová; Christina Popa; Rudolf Rumetshofer; Alena Skrahina; Varvara Solodovnikova; Victor Spinu; Simon Tiberi; Piret Viiklepp; Frank van Leth; for TBnet

doi:10.1183/13993003.02363-2016

Treatment outcomes of MDR-TB and HIV co-infection in Europe

Eur Respir J. 2017 Jun 8;49(6):1602363. doi: 10.1183/13993003.02363-2016. Print 2017 Jun.

Authors

Cecile Magis-Escurra^{1

2}, Gunar Günther^{3

4

2}, Christoph Lange^{5

4

6

7

2}, Sofia Alexandru⁸, Neus Altet⁹, Korkut Avsar¹⁰, Didi Bang¹¹, Raisa Barbuta¹², Graham Bothamley¹³, Ana Ciobanu⁸, Valeriu Crudu^{8

14}, Manfred Davilovits¹⁵, Martin Dedicoat^{16

17}, Raquel Duarte^{18

19}, Gina Gualano²⁰, Heike Kunst^{21

22}, Wiel de Lange^{23

24}, Vaira Leimane²⁵, Anne-Marie McLaughlin²⁶, Inge Muylle²⁷, Veronika Polcová²⁸, Christina Popa²⁹, Rudolf Rumetshofer³⁰, Alena Skrahina³¹, Varvara Solodovnikova³¹, Victor Spinu²⁹, Simon Tiberi^{22

32

33}, Piret Viiklepp³⁴, Frank van Leth^{35

36

2}; for TBnet

Affiliations

¹ Radboud University Medical Centre - TB Expert Centre UCCZ Dekkerswald, Nijmegen-Groesbeek, The Netherlands.
² These authors contributed equally to this article.
³ Research Center Borstel, Clinical Infectious Diseases, German Center for Infection Research (DZIF), Borstel, Germany.
⁴ Dept of Medicine, University of Namibia School of Medicine, Windhoek, Namibia.
⁵ Research Center Borstel, Clinical Infectious Diseases, German Center for Infection Research (DZIF), Borstel, Germany clange@fz-borstel.de.
⁶ International Health/Infectious Diseases, University of Lübeck, Lübeck, Germany.
⁷ Dept of Medicine, Karolinska Institute, Stockholm, Sweden.
⁸ Institute of Phthisiopneumology, Chisinau, Moldova.
⁹ Hospital Universitari Vall d'Hebron, Research Institute-IDIAP Jordi Gol, Barcelona, Spain.
¹⁰ Asklepios Klinik Gauting, Gauting, Germany.
¹¹ Statens Serum Institut, Copenhagen, Denmark.
¹² Balti Municipal Hospital, Balti, Republic of Moldova.
¹³ Homerton University Hospital, London, UK.
¹⁴ National TB Reference Laboratory, Chisinau, Republic of Moldova.
¹⁵ Dept of Respiratory Medicine, Tartu University Lung Hospital, Tartu, Estonia.
¹⁶ Heart of England Foundation Trust, Birmingham, UK.
¹⁷ University of Warwick, Coventry, UK.
¹⁸ EpiUnit, Institute of Public Health, Porto University, Porto, Portugal.
¹⁹ Dept of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Porto, Portugal.
²⁰ National Institute for Infectious Diseases "L. Spallanzani" (INMI), Rome, Italy.
²¹ Dept of Medicine, Queen Mary University, London, UK.
²² Barts Health NHS Trust, London, UK.
²³ University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
²⁴ Tuberculosis Centre Beatrixoord, Haren, The Netherlands.
²⁵ Riga East University Hospital, Tuberculosis and Lung Diseases Centre, Riga, Latvia.
²⁶ St James's Hospital, Dublin, Ireland.
²⁷ Dept of Respiratory Medicine, University Medical Center St Pieter, Brussels, Belgium.
²⁸ Thomayer University Hospital, Prague, Czech Republic.
²⁹ Marius-Nasta-Institut, Bucharest, Romania.
³⁰ Otto Wagner Hospital, Vienna, Austria.
³¹ Clinical Dept, Republican Research and Practical Centre for Pulmonology and Tuberculosis, Minsk, Belarus.
³² AOVV E, Morelli Reference Hospital for MDR and HIV-TB, Sondalo, Italy.
³³ Dept of Infectious Diseases, Queen Mary University, London, UK.
³⁴ National Institute for Health Development, Tallinn, Estonia.
³⁵ Dept of Global Health, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
³⁶ Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.

PMID: 28596434
DOI: 10.1183/13993003.02363-2016

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antitubercular Agents / therapeutic use*
Coinfection / drug therapy
Coinfection / microbiology
Coinfection / virology
Communicable Disease Control / standards
Data Collection
Disease-Free Survival
Europe
Germany
HIV Infections / complications*
HIV Infections / drug therapy*
HIV Infections / epidemiology
Humans
Kaplan-Meier Estimate
Patient Outcome Assessment*
Prevalence
Proportional Hazards Models
Regression Analysis
Risk
Tuberculosis, Multidrug-Resistant / complications*
Tuberculosis, Multidrug-Resistant / drug therapy*
Tuberculosis, Multidrug-Resistant / epidemiology

Substances

Antitubercular Agents