Unusual Fungal Lesion Presenting as a Neoplastic Pediatric Tongue Mass

Pediatrics. 2017 May;139(5):e20161345. doi: 10.1542/peds.2016-1345. Epub 2017 Apr 5.

Abstract

Tongue lesions in the pediatric population are rare. The differential diagnosis of these lesions is broad, and rapid growth of the lesion is concerning for a neoplastic process. We present a rare case of a fungal lesion mimicking a neoplastic growth in a 22-month-old girl. She underwent complete excision successfully. Full evaluation for benign and malignant neoplasms was negative. Tissue culture demonstrated growth of a rare Candida species to be the cause of the lesion. Postoperatively, she continues to do well, without regrowth 6 months later. This case reinforces the role of tissue culture when histology fails to demonstrate a diagnosis and emphasizes the need for efficient communication between the pediatrician, otolaryngologist, and pathologist for timely excision.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Candida / isolation & purification*
  • Candidiasis / diagnosis*
  • Candidiasis / drug therapy
  • Diagnosis, Differential
  • Female
  • Humans
  • Infant
  • Tongue / microbiology
  • Tongue / pathology*
  • Tongue Neoplasms / diagnosis*

Substances

  • Antifungal Agents