Triterpenes from Pouteria ramiflora (Mart.) Radlk. Leaves (Sapotaceae)

Food Chem Toxicol. 2017 Nov;109(Pt 2):1063-1068. doi: 10.1016/j.fct.2017.05.026. Epub 2017 May 19.

Abstract

Pouteria ramiflora (Mart.) Radlk. (Sapotaceae) is a species used by inhabitants from the Cerrado for its edible fruits and medicinal value. Hexane crude extracts from leaves and fractions were evaluated for in vitro α-amylase inhibitory activity and antioxidant potential. The fraction with the highest α-amylase inhibitory activity was submitted to a phytochemical study. Three triterpenes were isolated, friedelin, epi-friedelanol, and taraxerol. This is the first report of these compounds isolated from P. ramiflora. Moreover, this is the first report of friedelin isolated from Pouteria sp. Epi-friedelanol was present in significant amounts, suggesting that this compound could be a candidate marker for this species.

Keywords: Cerrado; Epi-friedelanol; Friedelin; Pouteria ramiflora; Sapotaceae; Taraxerol.

MeSH terms

  • Animals
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / isolation & purification
  • Molecular Structure
  • Oleanolic Acid / analogs & derivatives
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification
  • Plant Extracts / chemistry*
  • Plant Extracts / isolation & purification
  • Plant Leaves / chemistry
  • Pouteria / chemistry*
  • Swine
  • Triterpenes / chemistry*
  • Triterpenes / isolation & purification
  • alpha-Amylases / antagonists & inhibitors
  • alpha-Amylases / chemistry

Substances

  • Antioxidants
  • Enzyme Inhibitors
  • Plant Extracts
  • Triterpenes
  • friedelinol
  • Oleanolic Acid
  • alpha-Amylases