Osteomyelitis

Infect Dis Clin North Am. 2017 Jun;31(2):325-338. doi: 10.1016/j.idc.2017.01.010.

Abstract

Osteomyelitis is an ancient disease with varied pathophysiology. The several clinical syndromes associated with bone infection have specific clinical presentations and microbiology. Successful recognition and management of the disease requires a knowledge of these mechanisms and the organisms most common in each. Diagnosis is made by a combination of clinical examination, supportive blood testing, and appropriate radiography. With these elements in place, patient presentation can be placed in the framework of a staging system, which often helps to suggest the appropriate mix of antimicrobial and surgical therapies.

Keywords: Diabetic foot infection; Hematogenous osteomyelitis; MRSA; Osteomyelitis; Traumatic osteomyelitis.

Publication types

  • Review

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Diabetic Foot / complications
  • Diabetic Foot / microbiology
  • Female
  • Humans
  • Male
  • Methicillin-Resistant Staphylococcus aureus / drug effects
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification
  • Osteomyelitis / diagnosis*
  • Osteomyelitis / drug therapy
  • Osteomyelitis / therapy*
  • Radiography / methods
  • Staphylococcal Infections / diagnosis
  • Staphylococcal Infections / drug therapy

Substances

  • Anti-Bacterial Agents