Hydrocephalus: a rare initial manifestation of sporadic intramedullary hemangioblastoma : Intramedullary hemangioblastoma presenting as hydrocephalus

Childs Nerv Syst. 2017 Aug;33(8):1399-1403. doi: 10.1007/s00381-017-3415-0. Epub 2017 Apr 25.

Abstract

Background: Intramedullary hemangioblastomas are rare benign vascular tumors, infrequent in pediatric patients. Clinical symptoms vary according to the age of presentation, tumor size, location, and concomitant syringomyelia. This is the second reported case of hemangioblastoma presenting with acute hydrocephalus.

Case presentation: A 3-month-old infant with acute hydrocephalus was asymptomatic after a ventriculoperitoneal shunt was placed. She returned 3 months later with irritability, acute paraplegia, and respiratory distress. Magnetic resonance imaging (MRI) showed an intramedullary T8-T9 tumor with syringomyelia. She underwent surgical resection with good results during the 6-month follow-up.

Conclusion: Intramedullary tumors may present as hydrocephalus and other nonspecific symptoms, with invariably delayed diagnosis in children, but must be considered in suspicious cases.

Keywords: Children; Hemangioblastoma; Hydrocephalus; Spinal cord tumor; Syringomyelia.

Publication types

  • Case Reports

MeSH terms

  • Antigens, CD34 / metabolism
  • Female
  • Hemangioblastoma / complications*
  • Hemangioblastoma / diagnostic imaging
  • Humans
  • Hydrocephalus / diagnostic imaging
  • Hydrocephalus / etiology*
  • Hydrocephalus / surgery*
  • Infant
  • Platelet Endothelial Cell Adhesion Molecule-1 / metabolism
  • Spinal Cord Neoplasms / complications*
  • Spinal Cord Neoplasms / diagnostic imaging
  • Tomography Scanners, X-Ray Computed

Substances

  • Antigens, CD34
  • Platelet Endothelial Cell Adhesion Molecule-1