Draft Genome Sequence of Bacillus cereus LA2007, a Human-Pathogenic Isolate Harboring Anthrax-Like Plasmids

Angela Pena-Gonzalez; Chung K Marston; Luis M Rodriguez-R; Cari B Kolton; Julia Garcia-Diaz; Amanda Theppote; Michael Frace; Konstantinos T Konstantinidis; Alex R Hoffmaster

doi:10.1128/genomeA.00181-17

Draft Genome Sequence of Bacillus cereus LA2007, a Human-Pathogenic Isolate Harboring Anthrax-Like Plasmids

Genome Announc. 2017 Apr 20;5(16):e00181-17. doi: 10.1128/genomeA.00181-17.

Authors

Affiliations

¹ School of the Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
² Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
³ School of Civil & Environmental Engineering, Georgia Institute of Technology, Atlanta, Georgia, USA.
⁴ Department of Infectious Diseases, Ochsner Clinic Foundation, New Orleans, Louisiana, USA.
⁵ Department of Internal Medicine, University of Queensland, Brisbane, Queensland, Australia.
⁶ Biotechnology Core Facility Branch, Division of Scientific Resources, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
⁷ Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA amh9@cdc.gov.

Abstract

We present the genome sequence of Bacillus cereus LA2007, a strain isolated in 2007 from a fatal pneumonia case in Louisiana. Sequence-based genome analysis revealed that LA2007 carries a plasmid highly similar to Bacillus anthracis pXO1, including the genes responsible for the production and regulation of anthrax toxin.