Hybridization chain reactions on silica coated Qbeads for the colorimetric detection of multiplex microRNAs

Qingsheng Guo; Feika Bian; Yuqian Liu; Xiaojun Qu; Xianyun Hu; Qingjiang Sun

doi:10.1039/c7cc00462a

Hybridization chain reactions on silica coated Qbeads for the colorimetric detection of multiplex microRNAs

Chem Commun (Camb). 2017 May 2;53(36):4954-4957. doi: 10.1039/c7cc00462a.

Authors

Qingsheng Guo¹, Feika Bian, Yuqian Liu, Xiaojun Qu, Xianyun Hu, Qingjiang Sun

Affiliation

¹ State Key Laboratory of Bioelectronics, School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, P. R. China. sunqj@seu.edu.cn.

PMID: 28422199
DOI: 10.1039/c7cc00462a

Abstract

A robust Qbead platform that integrated with target-binding, hybridization chain reaction and staining was developed for the direct multiplexed detection of endogenous miRNAs by amplified Qbead-colour change.

MeSH terms

Color
Colorimetry*
MicroRNAs / analysis*
Nucleic Acid Hybridization*
Optical Imaging
Particle Size
Quantum Dots*
Silicon Dioxide / chemistry*
Surface Properties

Substances

MicroRNAs
Silicon Dioxide