Nanoparticles for immune system targeting

Drug Discov Today. 2017 Sep;22(9):1295-1301. doi: 10.1016/j.drudis.2017.03.013. Epub 2017 Apr 5.

Abstract

Nanoparticles (NPs) are found in numerous applications used to modulate the immune system. They serve as drug delivery carriers or vaccine adjuvants and are utilized as therapeutics against a variety of diseases. NPs can be engineered to target distinct cellular components representing multiple pathways of immunity. The combination of NPs with immune system-targeting moieties has paved the way for improved targeted immune therapies. Here we provide an update of recent progress in this field.

Publication types

  • Review

MeSH terms

  • Adaptive Immunity / drug effects*
  • Animals
  • Drug Delivery Systems
  • Humans
  • Immunity, Innate / drug effects*
  • Nanoparticles / therapeutic use*