Electronic Medical Record-Integrated Pharmacogenomics and Related Clinical Decision Support Concepts

P J Caraballo; S J Bielinski; J L St Sauver; R M Weinshilboum

doi:10.1002/cpt.707

Electronic Medical Record-Integrated Pharmacogenomics and Related Clinical Decision Support Concepts

Clin Pharmacol Ther. 2017 Aug;102(2):254-264. doi: 10.1002/cpt.707. Epub 2017 May 26.

Authors

P J Caraballo^{1

2}, S J Bielinski³, J L St Sauver^{3

4}, R M Weinshilboum^{5

6}

Affiliations

¹ Division of General Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
² Office of Information and Knowledge Management, Mayo Clinic, Rochester, Minnesota, USA.
³ Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
⁴ Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA.
⁵ Division of Clinical Pharmacology, Departments of Molecular Pharmacology and Experimental Therapeutics & Medicine, Mayo Clinic, Rochester, Minnesota, USA.
⁶ Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, USA.

PMID: 28390138
DOI: 10.1002/cpt.707

Abstract

Advances in pharmacogenomics (PGx) have the potential to transform healthcare by allowing precision medicine to become a reality. However, PGx knowledge is new, complex, and evolving, and relying on the cognition of clinicians alone is insufficient for clinical implementation. Integrating clinical decision support (CDS) tools in the electronic health record (EHR) is critical for translating PGx into clinical practice. Herein, we review current strategies to implement PGx using EHR-CDS functionalities.

Publication types

Review

MeSH terms

Decision Support Systems, Clinical* / trends
Electronic Health Records* / trends
Humans
Pharmacogenetics / methods*
Pharmacogenetics / trends
Precision Medicine / methods*
Precision Medicine / trends