Degradation of Marine Algae-Derived Carbohydrates by Bacteroidetes Isolated from Human Gut Microbiota

Mar Drugs. 2017 Mar 24;15(4):92. doi: 10.3390/md15040092.

Abstract

Carrageenan, agarose, and alginate are algae-derived undigested polysaccharides that have been used as food additives for hundreds of years. Fermentation of dietary carbohydrates of our food in the lower gut of humans is a critical process for the function and integrity of both the bacterial community and host cells. However, little is known about the fermentation of these three kinds of seaweed carbohydrates by human gut microbiota. Here, the degradation characteristics of carrageenan, agarose, alginate, and their oligosaccharides, by Bacteroides xylanisolvens, Bacteroides ovatus, and Bacteroides uniforms, isolated from human gut microbiota, are studied.

Keywords: Bacteroides ovatus; Bacteroides uniforms; Bacteroides xylanisolvens; agarose; alginate; carrageenan; oligosaccharides.

MeSH terms

  • Alginates / metabolism
  • Aquatic Organisms / metabolism*
  • Bacteroidetes / metabolism*
  • Carrageenan / metabolism
  • Fermentation / physiology
  • Gastrointestinal Microbiome / physiology*
  • Glucuronic Acid / metabolism
  • Hexuronic Acids / metabolism
  • Humans
  • Microbiota / physiology
  • Oligosaccharides / metabolism*
  • Polysaccharides / metabolism*
  • Seaweed / metabolism*
  • Sepharose / metabolism

Substances

  • Alginates
  • Hexuronic Acids
  • Oligosaccharides
  • Polysaccharides
  • Glucuronic Acid
  • Carrageenan
  • Sepharose