[Well-being in adulthood of patients with chronic conditions in childhood: The GEDEPAC-2 questionnaire]

Rev Epidemiol Sante Publique. 2017 Apr;65(2):137-148. doi: 10.1016/j.respe.2017.01.001. Epub 2017 Feb 27.
[Article in French]

Abstract

Background: In France, chronic diseases affect 3 million children. In children with chronic conditions, long-term somatic outcome has been well described, but little is known about the psychosocial aspects of well-being.

Methods: Our aim was to build a self-administered questionnaire of global well-being in adults who had a chronic disease since or during childhood using a multidimensional and nonspecific approach. The questionnaire was constructed by a multidisciplinary group (epidemiologists, clinicians, sociologist, statistician). Items were built in compliance with reference data from the French general population (national surveys, free access) to allow comparative analysis adjusted for age and sex (and eventually other confounding factors) by indirect standardization (qualitative variables) or Z-scores (quantitative variables).

Results: The GEDEPAC-2 includes 108 items exploring 11 domains: education, employment, housing, material security, social links, civic engagement, leisure, environment, physical health/risky behavior, health-related quality of life and sex life. Factual questions and satisfaction scales jointly explore social well-being. Quality of life is analyzed in terms of physical quality of life, mental quality of life, fatigue and burden of treatment by 3 questionnaires validated in French (SF-12; MFI-20; Burden of Treatment Questionnaire). Experience of transition from pediatric to adult healthcare is described in 21 items. Paper and electronic versions were developed.

Conclusion: Built in a multidimensional approach to well-being and in line with the available reference data, GEDEPAC-2 will facilitate the implementation of future studies on impact in adulthood of chronic disease in childhood.

Keywords: Child; Chronic disease; Enfant; Maladie chronique; Participation sociale; Quality of life; Qualité de vie; Questionnaires; Sexuality; Sexualité; Social participation; Transition aux soins pour adultes; Transition to adult care.

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Child
  • Child Welfare
  • Chronic Disease / epidemiology*
  • Chronic Disease / psychology*
  • Employment
  • Female
  • France / epidemiology
  • Humans
  • Male
  • Quality of Life*
  • Self Concept
  • Surveys and Questionnaires
  • Transition to Adult Care* / standards
  • Transition to Adult Care* / statistics & numerical data
  • Young Adult