Abstract
This study maps the cellular response to the WEE1 inhibitor and explores the contributions of p53 to its effect.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Cycle / drug effects
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Cell Cycle Proteins / antagonists & inhibitors*
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Cell Line, Tumor
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Enzyme Inhibitors / therapeutic use
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Humans
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Nuclear Proteins / antagonists & inhibitors*
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Practice Guidelines as Topic*
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Protein-Tyrosine Kinases / antagonists & inhibitors*
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Pyrazoles / therapeutic use*
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Pyrimidines / therapeutic use*
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Pyrimidinones
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Squamous Cell Carcinoma of Head and Neck / drug therapy*
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Squamous Cell Carcinoma of Head and Neck / pathology
Substances
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Cell Cycle Proteins
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Enzyme Inhibitors
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Nuclear Proteins
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Pyrazoles
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Pyrimidines
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Pyrimidinones
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Protein-Tyrosine Kinases
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WEE1 protein, human
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adavosertib