Subclinical measles infection in vaccinated seropositive individuals in arctic Greenland

Vaccine. 1989 Aug;7(4):345-8. doi: 10.1016/0264-410x(89)90199-0.

Abstract

Measles vaccination was performed in the arctic district of Scoresbysund, Greenland in 1968, which had never been exposed to natural measles. More than 90% of the total population was vaccinated and a 94-100% seroconversion was obtained. During a serological survey to examine the immunity status of the vaccinees, it was discovered that a temporary increase in measles antibodies took place in the majority of the population 2-4 years after the vaccination. This was not accompanied by clinically observed measles. Most likely, it was due to an inapparent measles infection in a population considered highly immune after vaccination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibodies, Viral / analysis
  • Arctic Regions
  • Enzyme-Linked Immunosorbent Assay
  • Greenland
  • Humans
  • Immunoglobulin G / analysis
  • Measles / immunology*
  • Measles Vaccine / immunology*
  • Serologic Tests
  • Time Factors
  • Vaccination

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Measles Vaccine