Uveal schwannoma in a brown-eyed dog

Vet Ophthalmol. 2018 Mar;21(2):205-209. doi: 10.1111/vop.12458. Epub 2017 Jan 17.

Abstract

An eleven-year-old, female spayed Boxer dog was diagnosed with a uveal schwannoma (formerly known as the spindle cell tumor of the blue-eyed dog or SCTBED) despite having a uniformly brown iris. The patient presented to emergency for ocular discomfort, and the right globe was subsequently enucleated due to glaucoma and submitted for histopathology. Upon histopathologic evaluation, a uveal schwannoma was diagnosed and confirmed with immunohistochemical staining. Complete metastatic evaluation 1 and 6 months after initial presentation did not reveal evidence of metastasis, and the dog remains systemically healthy. This case represents a unique variant of uveal schwannoma and is relevant because although the vast majority of these tumors occur in blue-eyed dogs, clinicians should not completely rule out this tumor as a differential based on the iris color.

Keywords: canine; intraocular; schwannoma; spindle cell tumor of blue-eyed dogs; tumor; uveal.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Dog Diseases / pathology
  • Dogs
  • Eye Color
  • Female
  • Neurilemmoma / pathology
  • Neurilemmoma / veterinary*
  • Uveal Neoplasms / pathology*
  • Uveal Neoplasms / veterinary*