Pediatric melanoma

Semin Pediatr Surg. 2016 Oct;25(5):290-298. doi: 10.1053/j.sempedsurg.2016.09.010. Epub 2016 Sep 20.

Abstract

Childhood melanoma is a rare pediatric malignancy, with fewer than 500 new diagnoses annually. The incidence is increasing, particularly in the adolescent population. This review highlights the epidemiology, clinical presentation, and histopathologic challenges of pediatric melanoma. Surgical resection remains the cornerstone for localized and regionally advanced disease. Adjuvant therapies, including current options and potential novel therapeutics for this unique population will be discussed.

Keywords: Melanoma; Pediatric.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Antineoplastic Agents / therapeutic use
  • Chemotherapy, Adjuvant
  • Child
  • Dermatologic Surgical Procedures
  • Humans
  • Lymph Node Excision
  • Melanoma* / diagnosis
  • Melanoma* / epidemiology
  • Melanoma* / pathology
  • Melanoma* / therapy
  • Neoplasm Staging
  • Pediatrics
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / epidemiology
  • Skin Neoplasms* / pathology
  • Skin Neoplasms* / therapy
  • United States / epidemiology

Substances

  • Antineoplastic Agents