Concerted Genetic Function in Blood Traits

Cell. 2016 Nov 17;167(5):1167-1169. doi: 10.1016/j.cell.2016.10.055.

Abstract

The hematopoietic system plays a major role in human health. Two studies by Astle et al. and Chen et al. published in this issue of Cell use genome-wide association and functional genomics approaches to provide deep insights into the role of genetic variants in hematological traits. We discuss these discoveries and future strategies toward completing our understanding of the genetic basis for variation in human traits.

Publication types

  • Research Support, N.I.H., Extramural
  • Review
  • Comment

MeSH terms

  • Genetic Predisposition to Disease
  • Genetic Variation
  • Genome-Wide Association Study*
  • Humans
  • Phenotype*
  • Polymorphism, Single Nucleotide