An overview of psoriatic arthritis - epidemiology, clinical features, pathophysiology and novel treatment targets

Wien Klin Wochenschr. 2016 Nov;128(21-22):791-795. doi: 10.1007/s00508-016-1111-9. Epub 2016 Nov 7.

Abstract

Psoriatic arthritis is a chronic inflammatory joint disease occurring in a subgroup of patients suffering from psoriasis. This article gives an overview of the complexity of psoriatic arthritis, looking at several aspects of this heterogeneous disease, such as epidemiology, important clinical features and comorbidities as well as current concepts of the pathophysiology and subsequent insights in novel treatment targets.

Keywords: Clinical aspects; Epidemiology; Pathophysiology; Psoriatic arthritis; Treatment.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Psoriatic / diagnosis*
  • Arthritis, Psoriatic / epidemiology
  • Arthritis, Psoriatic / therapy*
  • Comorbidity
  • Diagnosis, Differential
  • Evidence-Based Medicine
  • Humans
  • Incidence
  • Inflammation / diagnosis*
  • Inflammation / epidemiology
  • Inflammation / therapy*
  • Molecular Targeted Therapy / methods
  • Risk Factors
  • Symptom Assessment / methods*
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents