The emergence of intracellular metabolite signaling networks

Wei Xu; Jianyuan Zhao; Shimin Zhao

doi:10.1002/iub.1567

The emergence of intracellular metabolite signaling networks

IUBMB Life. 2016 Nov;68(11):871-872. doi: 10.1002/iub.1567. Epub 2016 Oct 20.

Authors

Wei Xu^{1

2}, Jianyuan Zhao³, Shimin Zhao^{4

5

6}

Affiliations

¹ The Obstetrics and Gynecology Hospital of Fudan University, Fudan University, Shanghai, 200011, People's Republic of China.
² Institutes of Biomedical Sciences, Fudan University, Shanghai, 200011, People's Republic of China.
³ School of Life Sciences, Fudan University, Shanghai, 200011, People's Republic of China.
⁴ The Obstetrics and Gynecology Hospital of Fudan University, Fudan University, Shanghai, 200011, People's Republic of China. zhaosm@fudan.edu.cn.
⁵ Institutes of Biomedical Sciences, Fudan University, Shanghai, 200011, People's Republic of China. zhaosm@fudan.edu.cn.
⁶ School of Life Sciences, Fudan University, Shanghai, 200011, People's Republic of China. zhaosm@fudan.edu.cn.

PMID: 27766754
DOI: 10.1002/iub.1567

Abstract

The signals of intracellular metabolites are integrated into cellular signaling networks by forming metabolite-derived posttranslational modifications or by non-covalently binding to proteins. These signals serve to coordinate cell metabolism and to regulate various aspects of cell physiology. © 2016 IUBMB Life, 68(11):871-872, 2016.

Keywords: cancer metabolism; metabolic enzymes; metabolite; metabolite signals.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Humans
Intracellular Signaling Peptides and Proteins / metabolism*
Protein Processing, Post-Translational
Signal Transduction*

Substances

Intracellular Signaling Peptides and Proteins