Use of Plant Extracts as an Effective Manner to Control Clostridium perfringens Induced Necrotic Enteritis in Poultry

Biomed Res Int. 2016:2016:3278359. doi: 10.1155/2016/3278359. Epub 2016 Sep 25.

Abstract

Necrotic enteritis (NE) is an important concern in poultry industry since it causes economic losses, increased mortality, reduction of bird welfare, and contamination of chicken products for human consumption. For decades, the use of in-feed antimicrobial growth promoters (AGPs) has been the main strategy to control intestinal pathogens including Clostridium perfringens (CP), the causative agent of NE. However, the use of AGPs in animal diet has been linked to the emergence and transmission of antimicrobial resistance through food-borne microorganisms, which has led to the ban of AGPs in many countries. This scenario has challenged the poultry industry to search for safer alternative products in order to prevent NE. In this context, the utilization of natural plant extracts with antimicrobial properties appears as a promising and feasible tool to control NE in chicken. In this paper, we review the scientific studies analyzing the potential of plant extracts as alternative feed additives to reduce NE in poultry, with focus on two types of plant products that arise as promising candidates: tannins and essential oils. Some of these products showed antimicrobial activity against CP and coccidia in vitro and in vivo and are able to increase productive performance, emulating the bioactive properties of AGPs.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / therapeutic use*
  • Clostridium Infections / drug therapy
  • Clostridium Infections / veterinary*
  • Clostridium perfringens / drug effects
  • Drug Resistance, Bacterial
  • Drug Tolerance
  • Enteritis / drug therapy*
  • Food Microbiology
  • Microbial Sensitivity Tests
  • Necrosis / drug therapy*
  • Oils, Volatile / chemistry*
  • Plant Extracts / chemistry*
  • Poultry
  • Poultry Diseases / drug therapy*
  • Tannins / chemistry*

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Oils, Volatile
  • Plant Extracts
  • Tannins