SERKing Coreceptors for Receptors

Trends Plant Sci. 2016 Dec;21(12):1017-1033. doi: 10.1016/j.tplants.2016.08.014. Epub 2016 Sep 19.

Abstract

Plants have evolved a large number of cell surface-resident receptor-like kinases (RLKs) and receptor-like proteins (RLPs), many of which are implicated in sensing extrinsic and intrinsic signals, and govern diverse cellular responses. The signaling pathways mediated by RLKs and RLPs converge at a small group of RLKs, somatic embryogenesis receptor kinases (SERKs), via ligand-induced heterodimerization and transphosphorylation. As shared coreceptors in diverse signaling receptorsomes, SERKs exhibit functional plasticity yet maintain a high degree of signaling specificity. Here, we review recent advances in newly identified SERK functions in plant cell differentiation, growth, and immunity; discuss the regulation and activation mechanisms of SERK-associated receptorsomes; and provide insights into how SERKs maintain signaling specificity as convergent hubs in various signaling pathways.

Keywords: plant growth and development; plant immunity; receptor-like kinases (RLKs); receptor-like proteins (RLPs); somatic embryogenesis receptor kinases (SERKs).

Publication types

  • Review

MeSH terms

  • Gene Expression Regulation, Plant
  • Plant Proteins / genetics
  • Plant Proteins / metabolism*
  • Protein Kinases / genetics
  • Protein Kinases / metabolism
  • Protein Serine-Threonine Kinases / genetics
  • Protein Serine-Threonine Kinases / metabolism
  • Signal Transduction / genetics
  • Signal Transduction / physiology*

Substances

  • Plant Proteins
  • Protein Kinases
  • Protein Serine-Threonine Kinases