Polymer Physics of the Large-Scale Structure of Chromatin

Methods Mol Biol. 2016:1480:201-6. doi: 10.1007/978-1-4939-6380-5_17.

Abstract

We summarize the picture emerging from recently proposed models of polymer physics describing the general features of chromatin large scale spatial architecture, as revealed by microscopy and Hi-C experiments.

Keywords: Chromatin; Chromosome; Microscopy; Polymer physics.

MeSH terms

  • Biopolymers / chemistry*
  • Biopolymers / genetics
  • Cell Nucleus / chemistry
  • Cell Nucleus / genetics
  • Chromatin / chemistry*
  • Chromatin / genetics
  • Chromosomes / chemistry*
  • Chromosomes / genetics
  • Microscopy / methods*

Substances

  • Biopolymers
  • Chromatin