Evidence for Human Adaptation and Foodborne Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus

Clin Infect Dis. 2016 Nov 15;63(10):1349-1352. doi: 10.1093/cid/ciw532. Epub 2016 Sep 20.

Abstract

We investigated the evolution and epidemiology of a novel livestock-associated methicillin-resistant Staphylococcus aureus strain, which colonizes and infects urban-dwelling Danes even without a Danish animal reservoir. Genetic evidence suggests both poultry and human adaptation, with poultry meat implicated as a probable source.

Keywords: MRSA; foodborne transmission; host adaptation; livestock; poultry.

MeSH terms

  • Adult
  • Aged
  • Animals
  • DNA, Bacterial / genetics
  • Denmark
  • Female
  • Food Microbiology
  • Foodborne Diseases / microbiology*
  • Humans
  • Infant, Newborn
  • Livestock / microbiology*
  • Male
  • Methicillin-Resistant Staphylococcus aureus / genetics*
  • Middle Aged
  • Mink / microbiology
  • Polymorphism, Single Nucleotide / genetics
  • Poultry / microbiology
  • Retrospective Studies
  • Staphylococcal Infections* / microbiology
  • Staphylococcal Infections* / transmission
  • Staphylococcal Infections* / veterinary

Substances

  • DNA, Bacterial