Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera

Blood. 2016 Nov 3;128(18):2266-2270. doi: 10.1182/blood-2016-04-711283. Epub 2016 Sep 19.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Substitution
  • Cells, Cultured
  • Cohort Studies
  • DNA Mutational Analysis
  • Germ-Line Mutation*
  • Humans
  • Janus Kinase 2 / genetics*
  • Mutation, Missense*
  • Phenylalanine / genetics
  • Polycythemia Vera / genetics*
  • Polycythemia Vera / pathology
  • Polymorphism, Single Nucleotide
  • Valine / genetics

Substances

  • Phenylalanine
  • JAK2 protein, human
  • Janus Kinase 2
  • Valine