Premature Ventricular Complexes in Apparently Normal Hearts

Card Electrophysiol Clin. 2016 Sep;8(3):503-14. doi: 10.1016/j.ccep.2016.04.001. Epub 2016 Jun 22.

Abstract

Premature ventricular complexes (PVCs) are consistently associated with worse prognosis and higher morbidity and mortality. This article reviews PVCs and their presentation in patients with an apparently normal heart. Patients with PVCs may be completely asymptomatic, whereas others may note severely disabling symptoms. Cardiomyopathy may occur with frequent PVCs. Diagnostic work-up is directed at obtaining 12-lead ECG to characterize QRS morphology, Holter monitor to assess frequency, and echo and advanced imaging to assess for early cardiomyopathy and exclude structural heart disease. Options for management include watchful waiting, medical therapy, or catheter ablation. Malignant variants of PVCs may induce ventricular fibrillation even in a normal heart.

Keywords: Catheter ablation; Idiopathic ventricular fibrillation; PVC-induced cardiomyopathy.

Publication types

  • Review

MeSH terms

  • Cardiomyopathies
  • Catheter Ablation
  • Electrocardiography
  • Heart* / physiology
  • Heart* / physiopathology
  • Humans
  • Ventricular Fibrillation
  • Ventricular Premature Complexes* / diagnosis
  • Ventricular Premature Complexes* / physiopathology
  • Ventricular Premature Complexes* / surgery

Supplementary concepts

  • Paroxysmal ventricular fibrillation