Distinct Zika Virus Lineage in Salvador, Bahia, Brazil

Emerg Infect Dis. 2016 Oct;22(10):1788-92. doi: 10.3201/eid2210.160663. Epub 2016 Oct 15.

Abstract

Sequencing of isolates from patients in Bahia, Brazil, where most Zika virus cases in Brazil have been reported, resulted in 11 whole and partial Zika virus genomes. Phylogenetic analyses revealed a well-supported Bahia-specific Zika virus lineage, which indicates sustained Zika virus circulation in Salvador, Bahia's capital city, since mid-2014.

Keywords: Bahia; Brazil; ZIKV; Zika virus; capture probe enrichment; flaviviruses; metagenomic next-generation sequencing; molecular clock; mosquito-borne infections; outbreak surveillance; phylogenetic analysis; vector-borne infections; viral genome assembly; viruses.

MeSH terms

  • Adult
  • Aged
  • Brazil / epidemiology
  • DNA, Viral
  • Female
  • Genome, Viral
  • Humans
  • Male
  • Molecular Typing
  • Phylogeny
  • Sequence Analysis, DNA
  • Zika Virus / classification*
  • Zika Virus / genetics
  • Zika Virus Infection / epidemiology
  • Zika Virus Infection / virology*

Substances

  • DNA, Viral