Molecular Subtypes of Non-muscle Invasive Bladder Cancer

Seth P Lerner; A Gordon Robertson

doi:10.1016/j.ccell.2016.06.012

Molecular Subtypes of Non-muscle Invasive Bladder Cancer

Cancer Cell. 2016 Jul 11;30(1):1-3. doi: 10.1016/j.ccell.2016.06.012.

Authors

Seth P Lerner¹, A Gordon Robertson²

Affiliations

¹ Scott Department of Urology, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: slerner@bcm.edu.
² Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada.

PMID: 27411578
DOI: 10.1016/j.ccell.2016.06.012

Abstract

In this issue of Cancer Cell, Hedegaard et al. report a comprehensive multi-center transcriptional analysis of non-muscle invasive urothelial bladder cancer. They describe three molecular subtypes similar to those seen in other cohorts, as well as a unique CIS signature associated with risk of progression to muscle invasive cancer.

Publication types

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MeSH terms

Disease Progression
Humans
Neoplasm Invasiveness*
Urinary Bladder Neoplasms*