Metabolic syndrome and C reactive protein in patients undergoing angiography: Inevitable association?

Diabetes Metab Syndr. 2017 Apr-Jun;11(2):89-93. doi: 10.1016/j.dsx.2016.06.022. Epub 2016 Jun 18.

Abstract

Background: The Metabolic Syndrome (MS) is characterized by a set of risk factors, which causes metabolic and inflammatory changes that increase vascular risk and may promote the development of atherosclerosis. Changes in lifestyle are related to obesity and associated diseases such as hypertension, type 2 diabetes mellitus, MS and cardiovascular disease (CVD).

Aims: This study aimed to evaluate the relationship of MS components and high sensitivity C Reactive Protein (hsCRP) in patients undergoing arteriography.

Methods: A group of patients undergoing arteriography was recruited in order we could evaluate the metabolic profile, levels of hsCRP and number of obstructions in the arteries.

Results: Most of our patients underwent arteriography are more likely to have hypertension, glucose intolerance, dyslipidemia, and central obesity, thus, MS is prevalent in this group. They also tend to exhibit higher values of hsCRP, lower values ​​for the estimative of the size of the LDL-c particle and higher number of obstruction in the arteries.

Conclusion: We may say that the improvement of the above parameters could reduce inflammation and oxidative stress and vascular damages what would extend life expectancy and quality of life of this group of patients.

Keywords: Arteriography; C reactive protein; Glycaemia; Lipids; Metabolic syndrome; Obesity.

MeSH terms

  • Adult
  • Aged
  • Brazil / epidemiology
  • C-Reactive Protein / metabolism*
  • Coronary Angiography
  • Female
  • Humans
  • Male
  • Metabolic Syndrome / blood*
  • Metabolic Syndrome / epidemiology
  • Middle Aged

Substances

  • C-Reactive Protein