Clinical Question: Nasal saline or intranasal corticosteroids to treat allergic rhinitis in children

J Okla State Med Assoc. 2016 Apr-May;109(4-5):152-3.

Abstract

Clinical question: In pediatric populations, is nasal saline irrigation as effective as intranasal corticosteroids at relieving allergic rhinitis symptoms?

Answer: No. Intranasal steroids are more effective than nasal saline alone to reduce symptoms of allergic rhinitis (AR) in children. Combination therapy further improves symptom reduction. LEVEL OF EVIDENCE FOR THE ANSWER: B SEARCH TERMS: Allergic Rhinitis, Nasal Saline, Nasal corticosteroids, children younger than age 18. DATE SEARCH WAS CONDUCTED: August and September 2014, October 2015.

Inclusion criteria: Meta-analyses, randomized controlled trials, systematic reviews, cohort studies, nasal spray, hypertonic saline solution, nasal lavage, rhinitis, intranasal administration, nasal saline, human, English language.

Exclusion criteria: Antihistamines, Adults, Articles older than 2008.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Administration, Intranasal
  • Adolescent
  • Adrenal Cortex Hormones / administration & dosage
  • Adrenal Cortex Hormones / pharmacology*
  • Child
  • Combined Modality Therapy
  • Humans
  • Nasal Lavage / methods*
  • Rhinitis, Allergic / drug therapy
  • Rhinitis, Allergic / therapy*
  • Sodium Chloride / therapeutic use*
  • Treatment Outcome*

Substances

  • Adrenal Cortex Hormones
  • Sodium Chloride