Bioanalytical method transfer considerations of chromatographic-based assays

Bioanalysis. 2016 Jul;8(13):1409-13. doi: 10.4155/bio.16.34. Epub 2016 Jun 9.

Abstract

Bioanalysis is an important part of the modern drug development process. The business practice of outsourcing and transferring bioanalytical methods from laboratory to laboratory has increasingly become a crucial strategy for successful and efficient delivery of therapies to the market. This chapter discusses important considerations when transferring various types of chromatographic-based assays in today's pharmaceutical research and development environment.

Keywords: Contract Research Organization (CRO); Sponsor; bioanalysis; good laboratory practices (GLPs); new chemical entity (NCE).

MeSH terms

  • Chromatography / methods*
  • Drug Discovery / methods
  • Drug Industry / methods
  • Laboratories
  • Outsourced Services / methods