Phylogenetic analysis of Newcastle disease viruses isolated from commercial poultry in Mozambique (2011-2016)

Virus Genes. 2016 Oct;52(5):748-53. doi: 10.1007/s11262-016-1362-6. Epub 2016 Jun 8.

Abstract

The complete sequence of the fusion (F) protein gene from 11 Newcastle disease viruses (NDVs) isolated from commercial poultry in Mozambique between 2011 and 2016 has been generated. The F gene cleavage site motif for all 11 isolates was (112)RRRKRF(117) indicating that the viruses are virulent. A phylogenetic analysis using the full F gene sequence revealed that the viruses clustered within genotype VIIh and showed a higher similarity to NDVs from South Africa, China and Southeast Asia than to viruses previously described in Mozambique in 1994, 1995 and 2005. The identification of these new NDVs has important implications for Newcastle disease management and control in Mozambique.

Keywords: Genotype VIIh; Mozambique; Newcastle disease; Phylogenetic analysis; Poultry.

MeSH terms

  • Animals
  • China
  • Genotype
  • Mozambique
  • Newcastle Disease / virology*
  • Newcastle disease virus / genetics*
  • Newcastle disease virus / isolation & purification*
  • Phylogeny
  • Poultry / virology*
  • Poultry Diseases / virology*
  • RNA, Viral / genetics
  • Sequence Analysis, DNA / methods
  • South Africa

Substances

  • RNA, Viral