Four series of heterocyclic compounds were obtained using Ugi-type multicomponent reactions (MCRs) with methyl 2-formylbenzoate as one of the starting materials. A facile and efficient one-pot procedure was suitable for all the MCRs under acidic conditions. This process provided access to four series of complex and potentially biologically active scaffolds.
Keywords: Cyclization; Heterocycles; Intramolecular amidation; MCRs; One-pot procedure; UDC strategy; Ugi-type multicomponent reactions.