Xenograft-directed personalized therapy for a patient with post-transplant relapse of ALL

T N Trahair; R B Lock; R Sutton; K C S Sia; K Evans; J Richmond; T Law; N C Venn; J A Irving; S Moore; E Nievergall; P Dang; S L Heatley; D L White; T Revesz

doi:10.1038/bmt.2016.122

Xenograft-directed personalized therapy for a patient with post-transplant relapse of ALL

Bone Marrow Transplant. 2016 Sep;51(9):1279-82. doi: 10.1038/bmt.2016.122. Epub 2016 May 16.

Authors

T N Trahair^{1

2

3}, R B Lock^{2

3}, R Sutton^{2

3}, K C S Sia^{2

3}, K Evans², J Richmond², T Law², N C Venn², J A Irving⁴, S Moore⁵, E Nievergall^{6

7}, P Dang⁶, S L Heatley^{6

7}, D L White^{6

7

8}, T Revesz^{8

9}

Affiliations

¹ Kids Cancer Centre, Sydney Children's Hospital, High Street, Randwick, NSW, Australia.
² Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Australia, NSW, Sydney, Australia.
³ School of Women's and Children's Health, UNSW Australia, Sydney, NSW Australia.
⁴ Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.
⁵ Department of Genetic Pathology, SA Pathology, Adelaide, SA, Australia.
⁶ South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.
⁷ Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia.
⁸ Discipline of Paediatrics, University of Adelaide, Adelaide, SA, Australia.
⁹ SA Pathology (at Women's and Children's Hospital), Adelaide, SA, Australia.

PMID: 27183096
DOI: 10.1038/bmt.2016.122

No abstract available

Publication types

Case Reports
Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bone Marrow Transplantation
Child, Preschool
Female
Heterografts
Humans
Mice
Precision Medicine / methods*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
Recurrence

Grants and funding

N01CM42216/CA/NCI NIH HHS/United States