Understanding How Zika Virus Enters and Infects Neural Target Cells

Jonathan J Miner; Michael S Diamond

doi:10.1016/j.stem.2016.04.009

Understanding How Zika Virus Enters and Infects Neural Target Cells

Cell Stem Cell. 2016 May 5;18(5):559-60. doi: 10.1016/j.stem.2016.04.009.

Authors

Jonathan J Miner¹, Michael S Diamond²

Affiliations

¹ Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
² Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: diamond@borcim.wustl.edu.

PMID: 27152436
DOI: 10.1016/j.stem.2016.04.009

Abstract

Zika virus is a mosquito-transmitted flavivirus that has become a public health concern because of its ability to cause microcephaly. In this issue of Cell Stem Cell, Tang et al. (2016) and Nowakowski et al. (2016) use human neural stem cell models and single-cell RNA sequencing to investigate Zika virus tropism and potential entry receptors.

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MeSH terms

Base Sequence
Humans
Sequence Analysis, RNA
Zika Virus Infection*
Zika Virus*