FGFR1 N546K and H3F3A K27M mutations in a diffuse leptomeningeal tumour with glial and neuronal markers

Histopathology. 2016 Oct;69(4):704-7. doi: 10.1111/his.12983. Epub 2016 Jul 4.

Authors

Kyle Dyson¹, Marie Rivera-Zengotita², Jesse Kresak^{1

2}, Kristin Weaver¹, Brian Stover³, John Fort³, Maryam Rahman¹, David W Pincus¹, Elias J Sayour^{1

3}

Affiliations

¹ Department of Neurosurgery, Preston A. Wells, Jr Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Gainesville, FL, USA.
² Department of Pathology, University of Florida, Gainesville, FL, USA.
³ Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of Florida, Gainesville, FL, USA.

PMID: 27061725
DOI: 10.1111/his.12983

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adolescent
DNA Mutational Analysis
Glioma / genetics*
Glioma / pathology
Histones / genetics*
Humans
Male
Meningeal Neoplasms / genetics*
Meningeal Neoplasms / pathology
Mutation
Receptor, Fibroblast Growth Factor, Type 1 / genetics*

Substances

H3-3A protein, human
Histones
FGFR1 protein, human
Receptor, Fibroblast Growth Factor, Type 1