Treatment options for apnoea of prematurity

Arch Dis Child Fetal Neonatal Ed. 2016 Jul;101(4):F352-6. doi: 10.1136/archdischild-2015-310228. Epub 2016 Mar 22.

Abstract

Apnoea of prematurity (AOP) affects almost all infants born at <28 weeks gestation or with birth weight <1000 g. When untreated, AOP may be associated with negative outcomes. Because of these negative outcomes, effective treatment for AOP is an important part of optimising care of preterm infants. Standard treatment usually involves xanthine therapy and respiratory support. Cutting-edge work with stochastic vibrotactile stimulation and new pharmaceutical agents continues to expand therapeutic options. In this article, we review the pathophysiology of AOP, associated conditions and treatment options.

Keywords: Apnea of prematurity; Intensive care, neonatal; review article.

Publication types

  • Review

MeSH terms

  • Apnea* / diagnosis
  • Apnea* / etiology
  • Apnea* / physiopathology
  • Apnea* / therapy
  • Disease Management
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Infant, Premature, Diseases* / diagnosis
  • Infant, Premature, Diseases* / physiopathology
  • Infant, Premature, Diseases* / therapy