Cytoreductive Surgery Plus Platinum-Based Hyperthermic Intraperitoneal Chemotherapy in Epithelial Ovarian Cancer: A Promising Integrated Approach to Improve Locoregional Control

Marco Petrillo; Luigi Pedone Anchora; Giovanni Scambia; Anna Fagotti

doi:10.1634/theoncologist.2015-0500

Cytoreductive Surgery Plus Platinum-Based Hyperthermic Intraperitoneal Chemotherapy in Epithelial Ovarian Cancer: A Promising Integrated Approach to Improve Locoregional Control

Oncologist. 2016 May;21(5):532-4. doi: 10.1634/theoncologist.2015-0500. Epub 2016 Mar 23.

Authors

Marco Petrillo¹, Luigi Pedone Anchora¹, Giovanni Scambia¹, Anna Fagotti²

Affiliations

¹ Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.
² Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy Department of Surgery, Division of Minimally Invasive Gynecology, University of Perugia, Perugia, Italy annafagotti@libero.it.

Abstract

Epithelial ovarian cancer (EOC) remains the most lethal among gynecological malignancies. Evidence strongly suggests that administration of platinum-based hyperthermic intraperitoneal chemotherapy after cytoreductive surgery may represent an effective strategy to adequately treat both visible and microscopic disease, thus improving locoregional control.

MeSH terms

Carcinoma, Ovarian Epithelial
Combined Modality Therapy
Cytoreduction Surgical Procedures*
Female
Humans
Hyperthermia, Induced*
Neoplasms, Glandular and Epithelial / drug therapy*
Neoplasms, Glandular and Epithelial / pathology
Neoplasms, Glandular and Epithelial / surgery*
Ovarian Neoplasms / drug therapy*
Ovarian Neoplasms / pathology
Ovarian Neoplasms / surgery*
Platinum / therapeutic use

Substances

Platinum