A membrane-anchored fluorescent probe for detecting K(+) in the cell microenvironment

Mengyi Xiong; Huijie Zhu; Qiming Rong; Chan Yang; Liping Qiu; Xiao-Bing Zhang; Weihong Tan

doi:10.1039/c6cc00192k

A membrane-anchored fluorescent probe for detecting K(+) in the cell microenvironment

Chem Commun (Camb). 2016 Mar 28;52(25):4679-82. doi: 10.1039/c6cc00192k.

Authors

Mengyi Xiong¹, Huijie Zhu¹, Qiming Rong¹, Chan Yang¹, Liping Qiu¹, Xiao-Bing Zhang¹, Weihong Tan¹

Affiliation

¹ Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Collaborative Innovation Center for Chemistry and Molecular Medicine, Hunan University, Changsha 410082, P. R. China. xbzhang@hnu.edu.cn.

PMID: 26952866
DOI: 10.1039/c6cc00192k

Abstract

Cell-surface fluorescent probes are effective tools in cell biology and engineering. Here, we for the first time report a diacyllipid-aptamer conjugate-based fluorescent probe which could anchor on cell membrane for real-time tracking of potassium ions in the cell microenvironment.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aptamers, Nucleotide / chemistry
Cell Membrane / chemistry*
Cellular Microenvironment*
Fluorescent Dyes / chemistry*
Fluorescent Dyes / metabolism
Humans
Ions
Models, Biological
Potassium / chemistry*

Substances

Aptamers, Nucleotide
Fluorescent Dyes
Ions
Potassium