Many patients with Lewy body disease complain of pain, and their pain may be associated with this disease. Recently, pain has become a focus of attention in Parkinson's disease, but there is little information regarding pain in patients who have dementia with Lewy bodies. We used pregabalin to treat three Lewy body disease patients with chronic pain that may have been related to degeneration of central neurons. All three patients responded well to pregabalin at 25-50 mg/day. To our knowledge, there have been no previous reports of pregabalin showing efficacy for central neuropathic pain in Parkinson's disease or Lewy body disease.
Keywords: Lewy body disease; Parkinson's disease; central pain; dementia with Lewy bodies; neuropathic pain; pregabalin.
© 2016 The Authors. Psychogeriatrics © 2016 Japanese Psychogeriatric Society.