MET 14 Deletion in Sarcomatoid Non-Small-Cell Lung Cancer Detected by Next-Generation Sequencing and Successfully Treated with a MET Inhibitor

J Thorac Oncol. 2015 Dec;10(12):e113-4. doi: 10.1097/JTO.0000000000000645.

Authors

Carrie Lee¹, Dimitry Usenko, Garrett M Frampton, Caitlin McMahon, Siraj M Ali, Jared Weiss

Affiliation

¹ *Division of Hematology and Oncology, Linberger Comprehensive Cancer Center at the University of North Carolina, Chapel Hill, North Carolina; and †Research and Development, ‡Clinical Bioinformatics Operations, and §Clinical Development, Foundation Medicine Inc., Cambridge, Massachusetts.

PMID: 26709483
DOI: 10.1097/JTO.0000000000000645

No abstract available

Publication types

Case Reports

MeSH terms

Carcinoma, Non-Small-Cell Lung / genetics*
Gene Deletion
High-Throughput Nucleotide Sequencing
Humans
Lung Neoplasms / genetics*
Male
Middle Aged
Proto-Oncogene Proteins c-met / genetics*

Substances

MET protein, human
Proto-Oncogene Proteins c-met