Mussel-Inspired Polymer Carpets: Direct Photografting of Polymer Brushes on Polydopamine Nanosheets for Controlled Cell Adhesion

Adv Mater. 2016 Feb 17;28(7):1489-94. doi: 10.1002/adma.201504033. Epub 2015 Dec 15.

Abstract

2D mussel-inspired polydopamine (PDA) nanosheets are prepared and exploited as a functional surface for grafting various polymer brushes. The PDA nanosheet and its polymer-brush derivatives show lateral integrity and are robust; therefore, they can be detached from their substrates. Cell-adhesion tests show that the PDA nanosheet promotes cell growth and attachment, while a PDA-based poly(3-sulfopropyl methacrylate) carpet exhibits nonfouling behavior.

Keywords: 2D nanosheets; freestanding; nonfouling; polydopamine; polymer carpets.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biomimetic Materials / chemistry*
  • Biomimetic Materials / pharmacology*
  • Bivalvia*
  • Cell Adhesion / drug effects
  • Cell Line
  • Indoles / chemistry*
  • Indoles / pharmacology*
  • Methacrylates / chemistry
  • Mice
  • Nanostructures / chemistry*
  • Nylons / chemistry
  • Photochemical Processes*
  • Polymers / chemistry*
  • Polymers / pharmacology*
  • Polystyrenes / chemistry

Substances

  • Indoles
  • Methacrylates
  • Nylons
  • Polymers
  • Polystyrenes
  • poly(2-(dimethylamino)ethyl methacrylate)
  • polydopamine